Vitamin E

Vitamin E (Alfa-tocopherol)
fS-E- Vit KL 3169

Vitamin E (alfa-tocopherol) is a lipid-soluble vitamin that is one of the most important antioxidants in the body. It protects the cell membrane compounds, especially polyunsaturated fatty acids, from oxygenation caused by radicals. It also prevents the oxygenation LDL particles, and can protect tissues from heavy metal toxicity. Decreased vitamin E levels may indicate lipid absorption deficiency. Vitamin E levels are clearly elevated in familial hypercholesterolemia. Children and youth (younger than 19 yrs) have lower vitamin E levels than adults.

Indications

Investigating vitamin E deficiency or excessive intake.

Preparation

Blood sample. Requires 12 hours of fasting. Glass of water and usual medication are allowed.

No vitamin E supplements during 12 hours.

Sample

1 mL (minimum 0.5 mL) of serum or lithium heparin plasma (12 hours fasting). Protect from direct sunlight.

Storage and delivery

Delivery at room temperature on the sampling day. Store refrigerated over the weekend, ship at room temperature.

Method

Liquid chromatography (HPLC).

Turnaround time (weekdays)

5 – 10

Reference ranges

adults 8 – 48 µmol/L

Notes

The same sample may be used to test for vitamin A, KL 1113.

Inquiries

martin.tornudd@mineraalialboratoriomila.fi