Alanine aminotransferase
S-ALAT KL 1026
Serum ALAT is, in practice, a rather specific marker for liver cell damage. In acute hepatitis, both viral and medicine-induced, ALAT often increases by about tenfold or even more.
Moderate ALAT increase without liver damage can be seen in sepsis, pulmonary infarction, muscular dystrophies, cardiac insufficiency and renal insufficiency. Haemolytic samples can cause incorrectly high ALAT activities.
Indications
Diagnostics and monitoring of hepatic diseases.
Sample
1 mL of non-haemolysed serum (minimum 0.5 mL) or Li-heparin plasma.
Storage and delivery
Delivery at room temperature, if it arrives within 24 hours. Haemolysis interferes with the assay. Ship the sample as room-temperature, if it arrives within 24 hours. Can be stored refrigerated over the weekend.
Method
Photometric, in accordance with IFCC recommendation.
Turnaround time
1-2 weekdays
Reference ranges
children, 0 – 16 yrs |
below 40 |
U/L |
men, from 17 yrs |
10 – 70 |
U/L |
women, from 17 yrs |
10 – 45 |
U/L |
Inquiries
martin.tornudd@@milalab.fi